Structural and Chemical Biology Research Group

Introduction

Structural and Chemical Biology Research Group (SCBRG) brings together structural biologists, enzymologists, and drug designers in a format that includes journal club and seminar presentations. The SCBRG generally meets at 4:00PM Wednesdays in the Biochemistry conference room located at Stearns 704C. Seminars are sponsored by the Tufts Cancer Center and all are welcome to attend.

Aims

  • Provide a venue for the presentation of structural and chemical biology research from within Tufts University
  • Provide a platform for the discussion of new techniques, new advances, and interesting developments in the field outside Tufts
  • Aid in the growth of novice structural and chemical biologists by allowing them to: present and defend their own work to more experienced peers; learn of new, potentially important thesis-related techniques; and develop their skills for relating structural and chemical information to others in the field

SCBRG Member Research

Animation depicting Fusion loop 2 from Herpes Simplex Virus fusion glycoprotein B relocating to an alternate conformation as the pH is lowered.

Fusion loop 2 from Herpes Simplex Virus fusion glycoprotein B relocates to an alternate conformation as the pH is lowered, where it is anchored by a salt bridge between H263 and D226. Courtesy Samuel Stampfer from work published.