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Tufts University School of Medicine

Alan Kopin

Professor of Medicine
Department: Neuroscience
Programs: Genetics, Neuroscience
Laboratory: Tupper, 7th Floor

Alan Kopin

Professor of Medicine
Department: Neuroscience
Programs: Genetics, Neuroscience
Laboratory: Tupper, 7th Floor

Phone 617-636-4834
Lab phone: 617-636-8407
Office: Tupper, 7003
Campus: Boston

Links

Education

  • BA, Biology, Brown University
  • MD, University of North Carolina, Chapel Hill
  • Postdoctoral Training, Tufts University School of Medicine

Research synopsis

Our research interests are focused in molecular endocrinology with an emphasis on G protein-coupled receptors (GPCRs) We hope to define structure-function relationships of GPCRs including the identification of ligand binding determinants and the mechanisms of signal transduction. The laboratory has used this expertise to develop molecular tools to expedite GPCR drug discovery. Our research directions combine in vitro approaches with in vivo models (eg, knockout mice, transgenic drosophila) to define the physiologic functions mediated by GPCRs. The cholecystokinin/gastrin, dopamine, serotonin, GABA-B, and opioid receptor families are currently under study.