Programs: Cell, Molecular & Developmental Biology, Neuroscience
- BA, Biochemistry, University of Virginia
- PhD, Neuroscience, Sackler School, Tufts University
- Postdoctoral Training, Stanford Medical School
Ion channel proteins form pores in the surface of living cells. When these pores are open, they create electrical currents that are essential to many biological processes including the generation of nerve impulses, muscle contraction, and the release of neurotransmitters. Our research focuses on a subset of these channels. We are examining the interplay between calcium channels and calcium-activated potassium channels as they gate together to regulate neurotransmitter release at nerve terminals, and we are examining changes in ion-channel expression associated with Alzheimer’s disease. Our work employs stem cell, molecular biological, electrophysiological, and computer modeling approaches.