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Tufts University School of Medicine

Madeleine Oudin

Assistant Professor of Biomedical Engineering
Programs: Cell, Molecular & Developmental Biology
Laboratory: Science & Engineering Complex - 139

Madeleine Oudin

Assistant Professor of Biomedical Engineering
Programs: Cell, Molecular & Developmental Biology
Laboratory: Science & Engineering Complex - 139

Phone 617-627-2580
Office: Science & Engineering Complex - 134
Campus: Medford

Links

Education

  • BSc, Biochemistry, McGill University
  • MSc, Pharmacology, Kings College, London
  • PhD, Neuroscience, Kings College, London
  • Postdoctoral Training, Massachusetts Institute of Technology

Research synopsis

The main goal of the lab is investigate the role of the extracellular matrix (ECM), and its associated components, in cancer metastasis and drug resistance. The ECM is required for morphogenesis and maintenance tissue integrity, and it acts as a key regulator and effector of both physiological and pathophysiological tissue function. We study cancer progression from the perspective of the ECM, focusing on how dynamic, bidirectional signaling between the ECM and cells regulates cell behavior in tumor, immune and stromal compartments. Our interdisciplinary approach will place the lab at the intersection of cell biology, translational research, and bioengineering, and we will implement innovative technologies such as intravital imaging, 3D CRISPR screens, microfluidics and implantable devices to support our research.