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Tufts University School of Medicine

Robert Braun

Professor of Medicine
Programs: Genetics
Laboratory: ERB 2065

Robert Braun

Professor of Medicine
Programs: Genetics
Laboratory: ERB 2065

Phone 207-288-6841
Lab phone: 207-288-6855
Office: ERB 2534
Campus: JAX - Bar Harbor, Maine

Education

  • BA, Chemistry & Mathematics, University of Colorado, Boulder
  • PhD, Microbiology, Sackler School, Tufts University
  • Postdoctoral Training, University of Washington, Seattle

Research synopsis

My lab is driven by a passion to understand the cell biological basis of gamete (sperm and egg) development. We study how germline stem cells balance self-renewal with differentiation. Stem cell self-renewal at the expense of differentiation can cause germ cell tumors while differentiation at the expense of self-renewal can cause sterility. Our long-term goal is to understand the mechanisms that regulate germline stem cell fate. In other work, we are studying the molecular function of the hormone testosterone in spermatogenesis with a focus on how the tight junctions between Sertoli cells are regulated by testosterone. Lastly, we are investigating molecular mechanisms of translational regulation, a major form of gene regulation in both male and female germ cells, during spermatogenesis.