Dr. Thanikachalam is a cardiovascular surgeon and a faculty at the Department of Public Health and Community Medicine. In the public health domain, his research interests are in population-based risk assessment, and in developing and implementing population-specific, cost-effective healthcare delivery models for the prevention and management of cardiovascular diseases (CVD). Thanikachalam is the lead investigator at Tufts University for the population-based study, the PURSE-HIS. PURSE-HIS is an ongoing study of 8080 participants to investigate the prevalence and progression of subclinical and overt CVD in urban and rural populations in South India. In addition, Thanikachalam’s group has developed a Community-based Chronic Care Model for primary and secondary prevention of CVD. Further, to extend the care model to underserved populations, the group has developed a mobile phone-based software application with cloud infrastructure to facilitate a community-based CVD prevention program with the help of non-traditional health workers. Thanikachalam’s additional research focus is in developing mobile-enabled, point-of-care technologies to facilitate more comprehensive, community-based CVD prevention and management strategies. Dr. Thanikachalam is the principal investigator of a NIH funded collaborative project with Massachusetts Institute of Technology to develop a wearable, cuff-less blood pressure monitoring device and a MIT-TATA Center funded project to develop a mobile phone-enabled peripheral neuropathy analyzer. He is currently the lead investigator for the clinical validation of other mobile enabled technologies such as, retinal camera, GynecCam and spirometer.
Lane KJ, Stokes E, Seto KC, Thanikachalam S, Thanikachalam M, Bell M. Associations between greenness, impervious surface area, and nighttime lights on biomarkers of vascular aging in Chennai, India. Environ Health Perspect. 2017 Aug 2;125(8).
Li Y, Lane KJ, Corlin L, Patton AP, Durant JL, Thanikachalam M, Woodin M, Wang M, Brugge D. Association of Long-Term Near-Highway Exposure to Ultrafine Particles with Cardiovascular Diseases, Diabetes and Hypertension. Int J Environ Res Public Health. 2017 Apr 26;14(5).
Sodium Intake, Blood Pressure and Dietary Sources of Sodium in an Adult South Indian Population. Annals of Global Health. Ravi S, Bermudez O, Harivanzan V, Chui KHK, Vasudevan P, Must A, Thanikachalam S, Thanikachalam M. Annals of Global Health. 2016; 82 (2): 242.
Thanikachalam S, Harivanzan V, Mahadevan MV, Murthy JSN, Anbarasi C, Saravanababu CS, Must A. Baliga RR, Abraham WT, Thanikachalam M. Population Study of Urban, Rural and Semi-Urban Regions for the Detection of Endovascular Disease and Prevalence of Risk Factors and Holistic Intervention Study (PURSE-HIS): Rationale, Study Design and Baseline Characteristics. Global Heart Journal. 2015; S2211-8160(14)02669-6.
Corlin L, Woodin M, Thanikachalam M, Lowe L, Brugge D. Evidence for the healthy immigrant effect in older Chinese immigrants: a cross-sectional study. BMC Public Health 2014;14:603. PMCID: PMC4067103